New research proves that the more germs a child is exposed to during early childhood, the better their immune system in later life
A recent study completed by researchers at the School of Medicine at the University of California found that being too clean could impair the skin’s ability to heal. The research gives gravitas to the “hygiene hypothesis”, first proposed in the 1980s, which suggests that early childhood exposure to bugs might “prime” the immune system to prevent allergies. It has been used to explain why increasing numbers of children in developed countries, where antibacterial sprays and wipes are common, suffer from allergies such as hay fever and eczema. One in three people in Britain suffer from allergies according to research conducted by the charity Allergy UK has found.
The San Diego-based team of researchers, led by Professor Richard Gallo, discovered that normal bacteria that live on the skin trigger a pathway that helps prevent inflammation when we get hurt. These bugs dampen down overactive immune responses which can cause cuts and grazes to swell or lead to rashes. Gallo claims that the common bacterial species, known as staphylococci, which can cause inflammation when under the skin, are “good bacteria” when on the surface, as they can reduce inflammation. By studying mice and human cells, researchers discovered that staphylococci reduce inflammation by making a molecule, called lipoteichoic acid (or LTA), which acted on keratinocytes, the main cell types found in the outer layer of the skin. Read the rest of this entry »